Stk4^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Stk4^m2Btlr
• Name: serine/threonine kinase 4; mutation 2, Bruce Beutler
• MGI ID: MGI:6200290
• Synonyms: stryker
• Gene: Stk4 Location: Chr2:163916033-163997444 bp, + strand Genetic Position: Chr2, 84.6 cM, cytoband H3
• Alliance: Stk4^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 164,083,688 (v38) on chromosome 2, or base pair 9,576 in the GenBank genomic region NC_000068 encoding Stk4. The mutation corresponds to residue 210 in the mRNA sequence NM_021420 within exon 3 of 11 total exons. The mutation results in substitution of lysine 58 for a premature stop codon (K59*) in the STK4 protein. (J:265237)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk4 Mutation: 72 strains or lines available

References

• Original: J:265237 Choi JH, et al., Mutagenetix entry for stryker. MGI Direct Data Submission. 2018
• All: 1 reference(s)