Ap3b1^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ap3b1^m2Btlr
• Name: adaptor-related protein complex 3, beta 1 subunit; mutation 2, Bruce Beutler
• MGI ID: MGI:6197805
• Synonyms: bella
• Gene: Ap3b1 Location: Chr13:94495468-94702825 bp, + strand Genetic Position: Chr13, 49.22 cM
• Alliance: Ap3b1^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 94,528,257 (v38) on chromosome 13, or base pair 169,678 in the GenBank genomic region NC_000079 encoding Ap3b1. The mutation corresponds to residue 2,847 in the mRNA sequence NM_009680 within exon 23 of 27 total exons. The mutation results in an arginine to serine substitution at position 901 (R901S) in the AP3B1 protein. (J:264641)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ap3b1 Mutation: 95 strains or lines available

References

• Original: J:264641 Reyna C, et al., Mutagenetix entry for bella. MGI Direct Data Submission. 2018
• All: 1 reference(s)