Maz^em#Mhll
Endonuclease-mediated Allele Detail

Summary

• Symbol: Maz^em#Mhll
• Name: MYC-associated zinc finger protein (purine-binding transcription factor); endonuclease-mediated mutation, Meade Haller
• MGI ID: MGI:6197212
• Synonyms: Maz delta
• Gene: Maz Location: Chr7:126621306-126626177 bp, - strand Genetic Position: Chr7, 69.28 cM, cytoband F4
• Alliance: Maz^em#Mhll page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR-targeting removed delete exons 2 through 4. Four alleles were generated with the exon 1 to exon 5 splice mutation and slightly different deletion points. The pound symbol (#) is used when lines are pooled. (J:257647)

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Maz Mutation: 21 strains or lines available

References

• Original: J:257647 Haller M, et al., 16p11.2 transcription factor MAZ is a dosage-sensitive regulator of genitourinary development. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1849-E1858
• All: 2 reference(s)