Creg1^em1Yal
Endonuclease-mediated Allele Detail

Summary

• Symbol: Creg1^em1Yal
• Name: cellular repressor of E1A-stimulated genes 1; endonuclease-mediated mutation 1, Ya-Ling Han
• MGI ID: MGI:6196852
• Gene: Creg1 Location: Chr1:165591327-165602878 bp, + strand Genetic Position: Chr1, 73.11 cM
• Alliance: Creg1^em1Yal page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready, No functional change)
• Mutation: Insertion
• CRISPR-targeting flanked exons 2 and 3 with loxP sites. (J:263073)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Creg1 Mutation: 7 strains or lines available

References

• Original: J:263073 Zhang QY, et al., The novel intracellular protein CREG inhibits hepatic steatosis, obesity, and insulin resistance. Hepatology. 2017 Sep;66(3):834-854
• All: 4 reference(s)