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Clmptm1Fgr
Targeted Allele Detail
Nomenclature
Symbol: Clmptm1Fgr
Name: CXADR-like membrane protein; targeted mutation 1, Fritz G Rathjen
MGI ID: MGI:6187714
Synonyms: Clmp-, Clmptm1a/Fgr
Gene: Clmp  Location: Chr9:40685962-40785319 bp, + strand  Genetic Position: Chr9, 21.42 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:258315
Parent Cell Line:  E14.1 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 1 was replaced with a loxP-flanked neomycin cassette. Absence of mRNA was confirmed in the brain and intestine by RT-PCR and qRT-PCR, respectively. Western blot analysis confirmed the absence of protein in the brain, intestine, and ureter. (J:258315)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 5 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Clmp Mutation:  182 strains or lines available
References
Original:  J:258315 Langhorst H, et al., The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Dis Model Mech. 2018 Feb 22;11(2)
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
11/26/2019
MGI 6.14
The Jackson Laboratory