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Il1rapem1Adiuj
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Il1rapem1Adiuj
Name: interleukin 1 receptor accessory protein; endonuclease-mediated mutation 1, MODEL-AD Center
MGI ID: MGI:6164025
Gene: Il1rap  Location: Chr16:26581704-26730117 bp, + strand  Genetic Position: Chr16, 18.21 cM, cytoband B2
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj Trem2em1Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/cas9 endonuclease-mediated genome editing is used to introduce a 387bp deletion in the first coding exon. The mutation is believed to generate a null allele. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Il1rap Mutation:  4 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory