Plcg2^em2Adiuj
Endonuclease-mediated Allele Detail

Summary

• Symbol: Plcg2^em2Adiuj
• Name: phospholipase C, gamma 2; endonuclease-mediated mutation 2, MODEL-AD Center
• MGI ID: MGI:6164019
• Gene: Plcg2 Location: Chr8:118225030-118361881 bp, + strand Genetic Position: Chr8, 64.26 cM
• Alliance: Plcg2^em2Adiuj page

Mutation origin

• Strain of Origin: B6(SJL)-Apoe^{tm1.1(APOE*4)Adiuj}/J

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: CRISPR/cas9 endonuclease mediated genome editing is used to delete 13 bp (nucleotides 1570 to 1582) creating a null allele. (J:101977)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Plcg2 Mutation: 74 strains or lines available

References

• Original: J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017
• All: 1 reference(s)