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Plcg2em2Adiuj
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Plcg2em2Adiuj
Name: phospholipase C, gamma 2; endonuclease-mediated mutation 2, MODEL-AD Center
MGI ID: MGI:6164019
Gene: Plcg2  Location: Chr8:117498291-117635142 bp, + strand  Genetic Position: Chr8, 64.26 cM
Mutation
origin
Strain of Origin:  B6(SJL)-Apoetm1.1(APOE*4)Adiuj/J
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsCRISPR/cas9 endonuclease mediated genome editing is used to delete 13 bp (nucleotides 1570 to 1582) creating a null allele. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Plcg2 Mutation:  46 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/11/2020
MGI 6.14
The Jackson Laboratory