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Gimap6tm1.1Gwb
Targeted Allele Detail
Nomenclature
Symbol: Gimap6tm1.1Gwb
Name: GTPase, IMAP family member 6; targeted mutation 1.1, Geoffrey W Butcher
MGI ID: MGI:6160453
Synonyms: GIMAP6fl
Gene: Gimap6  Location: Chr6:48701582-48708225 bp, - strand  Genetic Position: Chr6, 23.67 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:262059
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance gene cassette and a second loxP site into intron 3. The neo cassette was removed after subsequent flp-mediated recombination, leaving a conditional-ready allele with exons 2 and 3 floxed. (J:262059)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gimap6 Mutation:  8 strains or lines available
References
Original:  J:262059 Pascall JC, et al., GIMAP6 is required for T cell maintenance and efficient autophagy in mice. PLoS One. 2018;13(5):e0196504
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/18/2020
MGI 6.14
The Jackson Laboratory