TgTn(pb-sb-ITP)2mJcad
Transgene Detail

Summary

• Symbol: TgTn(pb-sb-ITP)2mJcad
• Name: transgenic transposon concatemer 2m, Juan Cadinanos
• MGI ID: MGI:6160080
• Synonyms: ITP2m
• Transgene: TgTn(pb-sb-ITP)2mJcad Location: unknown Genetic Position: Chr14, Syntenic
• Alliance: TgTn(pb-sb-ITP)2mJcad page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Transposon concatemer)
• Mutation: Insertion
• Mutation details: A transposon concatemer consisting of Piggybac and Sleeping Beauty terminal repeats flanking an adenovirus splice acceptor site and an engrailed 2 splice acceptor site flanking five bi-directional polyadenylation signals. The total cargo load of the transposon is 1.9 Kb. This line carries around 35 copies of the transposon. (J:244930)

Tumor Data

List all tumor models in MMHCdb carrying TgTn(pb-sb-ITP)2mJcad

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:244930 de la Rosa J, et al., A single-copy Sleeping Beauty transposon mutagenesis screen identifies new PTEN-cooperating tumor suppressor genes. Nat Genet. 2017 May;49(5):730-741
• All: 2 reference(s)