Tg(Nkx2-2-EGFP)2Mtse
Transgene Detail

Summary

• Symbol: Tg(Nkx2-2-EGFP)2Mtse
• Name: transgene insertion 2, Michael P Matise
• MGI ID: MGI:6158939
• Synonyms: Nkx2.2:EGFP, Tg(Nkx2.2-EGFP)2Mtse
• Transgene: Tg(Nkx2-2-EGFP)2Mtse Location: unknown
• Alliance: Tg(Nkx2-2-EGFP)2Mtse page

Transgene origin

• Strain of Origin: C57BL/6 or SJL

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Mutation details: The bacterial artificial chromosome (BAC) RP23-224O8, modified by GENSAT to insert the coding sequence for enhanced green fluorescent protein (EGFP) downstream of the 5' regulatory sequences of the mouse NK2 homeobox 2 gene (Nkx2.2), was obtained from CHORI and microinjected into the male pronuclei of fertilized oocytes. Founder line 2 exhibited the strongest EGFP expression. (J:214964)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

Notes

"BAC DNA was microinjected into the male pronucleus of fertilized oocytes from C57BL/6 mice crossed with SJL agouti mice." (J: J:214964)

References

• Original: J:214964 Clark JK, et al., Mammalian Nkx2.2+ perineurial glia are essential for motor nerve development. Dev Dyn. 2014 Sep;243(9):1116-29
• All: 1 reference(s)