Btn2a2^tm1.2Wrth
Targeted Allele Detail

Summary

• Symbol: Btn2a2^tm1.2Wrth
• Name: butyrophilin, subfamily 2, member A2; targeted mutation 1.2, Walter Reith
• MGI ID: MGI:6158673
• Gene: Btn2a2 Location: Chr13:23661846-23673027 bp, - strand Genetic Position: Chr13, 9.74 cM
• Alliance: Btn2a2^tm1.2Wrth page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232636
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6NTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: The promoter region and the first two exons were deleted by cre-mediated recombination of flanking loxP sites. (J:232636)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Btn2a2 Mutation: 42 strains or lines available

References

• Original: J:232636 Sarter K, et al., Btn2a2, a T cell immunomodulatory molecule coregulated with MHC class II genes. J Exp Med. 2016 Feb 8;213(2):177-87
• All: 1 reference(s)