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Kifbpem1Hmy
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Kifbpem1Hmy
Name: kinesin family binding protein; endonuclease mediated mutation 1, Heather Young
MGI ID: MGI:6150321
Synonyms: line 1
Gene: Kifbp  Location: Chr10:62558470-62579066 bp, - strand  Genetic Position: Chr10, 32.43 cM, cytoband B4
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsA deletion of exon 1 was generated by CRISPR/Cas9 mutagenesis. Western blotting showed an absence of encoded protein in newborn homozygous mice. (J:253679)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 47 assay results
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Kifbp Mutation:  4 strains or lines available
References
Original:  J:253679 Hirst CS, et al., Kif1bp loss in mice leads to defects in the peripheral and central nervous system and perinatal death. Sci Rep. 2017 Nov 30;7(1):16676
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory