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Tg(H2-Dd)28Bee
Transgene Detail
Nomenclature
Symbol: Tg(H2-Dd)28Bee
Name: transgene insertion 28 Friedrich Beermann
MGI ID: MGI:6120900
Synonyms: Floxed H-2Dd, loxDd Tg
Transgene: Tg(H2-Dd)28Bee  Location: unknown  
Transgene
origin
Strain of Origin:  (C57BL/6 x DBA/2)F2
Transgene
description
Transgene Type:    Transgenic (Conditional ready, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(H2-Dd)28Bee expresses 1 gene
 
Mutation detailsAn H2-D gene was flanked by loxP sites at the promoter region and the exons that encode the alpha1 and alpha2 domains. This line expressed H-2D at levels similar (80%) to B10.D2 (H-2) mice. Upon cre-mediated recombination, expression of H2-D is abolished. (J:72831)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:72831 Ioannidis V, et al., Cre Recombinase-Mediated Inactivation of H-2D(d) Transgene Expression: Evidence for Partial Missing Self-Recognition by Ly49A NK Cells. J Immunol. 2001 Dec 1;167(11):6256-62
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory