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Fmnl1tm1.2Sdb
Targeted Allele Detail
Nomenclature
Symbol: Fmnl1tm1.2Sdb
Name: formin-like 1; targeted mutation 1.2, Scott D Blystone
MGI ID: MGI:6119535
Gene: Fmnl1  Location: Chr11:103171107-103198901 bp, + strand  Genetic Position: Chr11, 66.71 cM, cytoband D
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:250144
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExons 4-6 were flanked by loxP sites. Beta-galactosidase reporter and neomycin selection cassettes, flanked by FRT sites, were inserted into intron 3. Flp-mediated recombination removed the reporter and selection cassettes. Cre-mediated recombination deleted exons 4-6. (J:250144)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Fmnl1 Mutation:  0 strains or lines available
References
Original:  J:250144 Miller MR, et al., Non-canonical activity of the podosomal formin FMNL1gamma supports immune cell migration. J Cell Sci. 2017 May 15;130(10):1730-1739
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory