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Upf3atm1.1Wilk
Targeted Allele Detail
Nomenclature
Symbol: Upf3atm1.1Wilk
Name: UPF3 regulator of nonsense transcripts homolog A (yeast); targeted mutation 1.1, Miles F Wilkinson
MGI ID: MGI:6117429
Synonyms: Upf3afl
Gene: Upf3a  Location: Chr8:13785615-13799193 bp, + strand  Genetic Position: Chr8, 6.38 cM, cytoband A2
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:234504
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 3 and an FRT flanked neomycin resistance gene cassette and loxP site were inserted downstream of exon 3. Flpe-mediated recombination removed the neomycin cassette. (J:234504)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Upf3a Mutation:  0 strains or lines available
References
Original:  J:234504 Shum EY, et al., The Antagonistic Gene Paralogs Upf3a and Upf3b Govern Nonsense-Mediated RNA Decay. Cell. 2016 Apr 7;165(2):382-95
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/30/2020
MGI 6.15
The Jackson Laboratory