Csgalnact2^tm1.2Staka
Targeted Allele Detail

Nomenclature

• Symbol: Csgalnact2^tm1.2Staka
• Name: chondroitin sulfate N-acetylgalactosaminyltransferase 2; targeted mutation 1.2, Satoru Takahashi
• MGI ID: MGI:6117386
• Synonyms: t2 KO
• Gene: Csgalnact2 Location: Chr6:118107452-118139140 bp, - strand Genetic Position: Chr6, 55.86 cM

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:256718
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Recombinase mediated recombination removed exon 1 and the neo cassette. (J:256718)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Csgalnact2 Mutation: 16 strains or lines available

References

• Original: J:256718 Shimbo M, et al., Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2. PLoS One. 2017;12(12):e0190333
• All: 1 reference(s)