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Csgalnact2tm1.2Staka
Targeted Allele Detail
Nomenclature
Symbol: Csgalnact2tm1.2Staka
Name: chondroitin sulfate N-acetylgalactosaminyltransferase 2; targeted mutation 1.2, Satoru Takahashi
MGI ID: MGI:6117386
Synonyms: t2 KO
Gene: Csgalnact2  Location: Chr6:118107452-118139140 bp, - strand  Genetic Position: Chr6, 55.86 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:256718
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6J
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA loxP site was inserted upstream of exon 1. An FRT- and loxP-flanked neo cassette was inserted downstream of exon 1. Recombinase mediated recombination removed exon 1 and the neo cassette. (J:256718)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Csgalnact2 Mutation:  16 strains or lines available
References
Original:  J:256718 Shimbo M, et al., Postnatal lethality and chondrodysplasia in mice lacking both chondroitin sulfate N-acetylgalactosaminyltransferase-1 and -2. PLoS One. 2017;12(12):e0190333
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/16/2021
MGI 6.16
The Jackson Laboratory