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Gripap1tm1Rlh
Targeted Allele Detail
Summary
Symbol: Gripap1tm1Rlh
Name: GRIP1 associated protein 1; targeted mutation 1, Richard L Huganir
MGI ID: MGI:6117099
Synonyms: Grasp1 KO
Gene: Gripap1  Location: ChrX:7656009-7686806 bp, + strand  Genetic Position: ChrX, 3.51 cM
Alliance: Gripap1tm1Rlh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:256043
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA neomycin resistance gene cassette was inserted into exon 6, creating a premature stop codon. Western blot analysis and immunohistochemistry confirmed the absence of intact protein. (J:256043)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Gripap1 Mutation:  7 strains or lines available
References
Original:  J:256043 Chiu SL, et al., GRASP1 Regulates Synaptic Plasticity and Learning through Endosomal Recycling of AMPA Receptors. Neuron. 2017 Mar 22;93(6):1405-1419.e8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory