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Tg(HCRT-lacZ)A3Stak
Transgene Detail
Summary
Symbol: Tg(HCRT-lacZ)A3Stak
Name: transgene insertion A3, Takeshi Sakurai
MGI ID: MGI:6115474
Synonyms: hOX-nlacZ Tg
Transgene: Tg(HCRT-lacZ)A3Stak  Location: unknown  
Alliance: Tg(HCRT-lacZ)A3Stak page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Reporter)
Mutation:    Insertion
 
Mutation detailsA fragment of human HCRT promoter, including the 3.15kb 5' flanking region and all of the 5' noncoding region of exon 1, was fused to a modified lacZ gene, which has an SV40 T antigen nuclear localization signal (nlacZ). Six lines were created, with lines A3 and J2 expressing lacZ specifically in the LHA/subthalamic region. (J:55659)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:55659 Sakurai T, et al., Structure and function of human prepro-orexin gene. J Biol Chem. 1999 Jun 18;274(25):17771-6
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory