Tg(Hdc-cre/ERT2)#Tcw
Transgene Detail

Summary

• Symbol: Tg(Hdc-cre/ERT2)#Tcw
• Name: transgene insertion, Timothy C Wang
• MGI ID: MGI:6113500
• Synonyms: Hdc-CreER^T2
• Transgene: Tg(Hdc-cre/ERT2)#Tcw Location: unknown
• Alliance: Tg(Hdc-cre/ERT2)#Tcw page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Tg(Hdc-cre/ERT2)#Tcw expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Hdc (MGI:96062)

• Mutation details: The Hdc-CreERT2 transgenic line was generated by using bacterial artificial chromosome (BAC) recombineering from cloneRP23-474H6. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:253885)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Hdc (mouse) Summary of all recombinase alleles driven by Hdc. Alliance mouse Hdc gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:253885 Chen X, et al., Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop. Cell Stem Cell. 2017 Dec 7;21(6):747-760.e7
• All: 3 reference(s)