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Tg(S100B-rtTA)1Wjt
Transgene Detail
Summary
Symbol: Tg(S100B-rtTA)1Wjt
Name: transgene insertion 1, Wesley Thompson
MGI ID: MGI:6111288
Transgene: Tg(S100B-rtTA)1Wjt  Location: unknown  
Alliance: Tg(S100B-rtTA)1Wjt page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Transactivator)
Mutation:    Insertion
 
Mutation detailsA 9.4 kb portion of the upstream regulatory sequence for human S100B was inserted upstream of the coding sequence for the reverse tetracycline transactivator (rtTA) and human growth hormone polyadenylation sequences. This construct was used to create transgenic mice. Five founders were generated but only one gave robust expression in Schwann cells. The other four lines were discarded. (J:109980)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:109980 Hayworth CR, et al., Induction of neuregulin signaling in mouse schwann cells in vivo mimics responses to denervation. J Neurosci. 2006 Jun 21;26(25):6873-84
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory