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Astn2ridge
Spontaneous Allele Detail
Nomenclature
Symbol: Astn2ridge
Name: astrotactin 2; ridge
MGI ID: MGI:6093704
Synonyms: ridge
Gene: Astn2  Location: Chr4:65380803-66404611 bp, - strand  Genetic Position: Chr4, 34.31 cM, cytoband C1
Mutation
origin
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Spontaneous (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation detailsThe molecular lesion is a a ~30 kb deletion that encompasses exon 5 and has endpoints within a pair of LINE elements. PCR typing showed that the ~30 kb deletion is present in both R1 ES cells and in 129X1/SvJ mice, but not in the closely related 129S1/SvlmJ or 129S6/SvEvTac strains. (J:228899)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Astn2 Mutation:  30 strains or lines available
References
Original:  J:228899 Chang H, et al., Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles. PLoS Genet. 2015 Sep;11(9):e1005532
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
01/16/2018
MGI 6.11
The Jackson Laboratory