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Pkn3tm1Ajmc
Targeted Allele Detail
Nomenclature
Symbol: Pkn3tm1Ajmc
Name: protein kinase N3; targeted mutation 1, Angus JM Cameron
MGI ID: MGI:5911981
Gene: Pkn3  Location: Chr2:30077684-30091022 bp, + strand  Genetic Position: Chr2, 21.13 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:229595
Parent Cell Line:  PRX-B6N (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exon 2 was replaced with a pgk-neo cassette via homologous recombination. (J:229595)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pkn3 Mutation:  31 strains or lines available
References
Original:  J:229595 Quetier I, et al., Knockout of the PKN Family of Rho Effector Kinases Reveals a Non-redundant Role for PKN2 in Developmental Mesoderm Expansion. Cell Rep. 2016 Jan 26;14(3):440-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/24/2020
MGI 6.15
The Jackson Laboratory