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Tg(Myh6-LDB3*S196L)93Mva
Transgene Detail
Nomenclature
Symbol: Tg(Myh6-LDB3*S196L)93Mva
Name: transgene insertion 93, Matteo Vatta
MGI ID: MGI:5910333
Transgene: Tg(Myh6-LDB3*S196L)93Mva  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6J
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-LDB3*S196L)93Mva expresses 1 gene
 
Mutation detailsThe human cardiac-specific isoform 4 cDNA containing a leucine for serine substitution at amino acid 196 (S196L) in exon 4 fused to a 6His-V5 tag is under the control of the mouse alpha-myosin heavy chain. Two lines were generated 93 and 94. Line 93 is entered as a representative line. (J:243711)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:243711 Li Z, et al., A ZASP missense mutation, S196L, leads to cytoskeletal and electrical abnormalities in a mouse model of cardiomyopathy. Circ Arrhythm Electrophysiol. 2010 Dec;3(6):646-56
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory