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Tg(Myh6-Snai1)B10Jcc
Transgene Detail
Summary
Symbol: Tg(Myh6-Snai1)B10Jcc
Name: transgene insertion B10, James C Cross
MGI ID: MGI:5906252
Synonyms: MHC-Snail
Transgene: Tg(Myh6-Snai1)B10Jcc  Location: unknown  
Alliance: Tg(Myh6-Snai1)B10Jcc page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Myh6-Snai1)B10Jcc expresses 1 gene
 
Mutation detailsThe mouse Snai1 cDNA is under the control of the cardiac specific mouse myosin heavy chain alpha promoter. Three lines were established: B10, B18 and B26. Founder lines B18 and B26 died from cardiac failure while B10 survived. This line has a copy number of 2. (J:126850)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:126850 Hesse M, et al., Dilated cardiomyopathy is associated with reduced expression of the cardiac sodium channel Scn5a. Cardiovasc Res. 2007 Aug 1;75(3):498-509
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory