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Nop53tm1Asuz
Targeted Allele Detail
Summary
Symbol: Nop53tm1Asuz
Name: NOP53 ribosome biogenesis factor; targeted mutation 1, Akira Suzuki
MGI ID: MGI:5906161
Synonyms: Pict1deltaexon1-2
Gene: Nop53  Location: Chr7:15671760-15680033 bp, - strand  Genetic Position: Chr7, 8.64 cM, cytoband A2
Alliance: Nop53tm1Asuz page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:241062
Parent Cell Line:  E14K (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA 1.3 kb genomic sequence representing parts of exon 1 and 2 was replaced with a neomycin resistance gene cassette. (J:241062)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nop53 Mutation:  28 strains or lines available
References
Original:  J:241062 Sasaki M, et al., Regulation of the MDM2-P53 pathway and tumor growth by PICT1 via nucleolar RPL11. Nat Med. 2011 Jul 31;17(8):944-51
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory