Pde6a^em1(IMPC)Mbp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Pde6a^em1(IMPC)Mbp
• Name: phosphodiesterase 6A, cGMP-specific, rod, alpha; endonuclease-mediated mutation 1, Mouse Biology Program, UC Davis
• MGI ID: MGI:5896441
• Gene: Pde6a Location: Chr18:61353387-61422995 bp, + strand Genetic Position: Chr18, 34.41 cM
• Alliance: Pde6a^em1(IMPC)Mbp page
• IMPC: Pde6a gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 6 and flanking splicing regions were constitutively deleted from the Pde6a gene using CRISPR/Cas9 gene editing technology in mouse zygotes. (J:94077)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Pde6a Mutation: 52 strains or lines available

References

• Original: J:94077 Mutant Mouse Regional Resource Centers, Information obtained from the Mutant Mouse Regional Resource Centers (MMRRC). Unpublished. 2004-2015
• All: 3 reference(s)