Pfkfb3^tm1Pec
Targeted Allele Detail

Summary

• Symbol: Pfkfb3^tm1Pec
• Name: 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3; targeted mutation 1, Peter Carmeliet
• MGI ID: MGI:5825519
• Synonyms: PFKFB3^lox
• Gene: Pfkfb3 Location: Chr2:11476241-11558882 bp, - strand Genetic Position: Chr2, 8.73 cM
• Alliance: Pfkfb3^tm1Pec page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:200070
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Exons 2-3 were flanked by loxP sites. (J:237983)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pfkfb3 Mutation: 36 strains or lines available

References

• Original: J:200070 De Bock K, et al., Role of PFKFB3-Driven Glycolysis in Vessel Sprouting. Cell. 2013 Aug 1;154(3):651-63
• All: 6 reference(s)