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Pltptm2.1Jia
Targeted Allele Detail
Nomenclature
Symbol: Pltptm2.1Jia
Name: phospholipid transfer protein; targeted mutation 2.1, Xian-cheng Jiang
MGI ID: MGI:5825236
Synonyms: Pltpflox-deltaneo
Gene: Pltp  Location: Chr2:164681438-164699628 bp, - strand  Genetic Position: Chr2, 85.27 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:318775
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation detailsA loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette and left exons 2 and 3 floxed. (J:239143, J:318775)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 1 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pltp Mutation:  23 strains or lines available
References
Original:  J:318775 Yazdanyar A, et al., Liver phospholipid transfer protein (PLTP) expression with a PLTP-null background promotes very low-density lipoprotein production in mice. Hepatology. 2012 Aug;56(2):576-84
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
06/23/2022
MGI 6.20
The Jackson Laboratory