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Col5a2tm1.2Dgr
Targeted Allele Detail
Nomenclature
Symbol: Col5a2tm1.2Dgr
Name: collagen, type V, alpha 2; targeted mutation 1.2, David S Greenspan
MGI ID: MGI:5817900
Gene: Col5a2  Location: Chr1:45374331-45503282 bp, - strand  Genetic Position: Chr1, 23.69 cM, cytoband C1
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223298
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprtb-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    The loxP flanked exon 1 was removed via cre-mediated recombination. (J:223298)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Mice Carrying this Mutation: 7 assay results
In Structures Affected by this Mutation: 6 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Col5a2 Mutation:  0 strains or lines available
References
Original:  J:223298 Park AC, et al., Homozygosity and Heterozygosity for Null Col5a2 Alleles Produce Embryonic Lethality and a Novel Classic Ehlers-Danlos Syndrome-Related Phenotype. Am J Pathol. 2015 Jul;185(7):2000-11
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory