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RhoTvrm334
Chemically induced Allele Detail
Nomenclature
Symbol: RhoTvrm334
Name: rhodopsin; translational research vision model 334
MGI ID: MGI:5810761
Gene: Rho  Location: Chr6:115931748-115940036 bp, + strand  Genetic Position: Chr6, 53.72 cM
Mutation
origin
Strain of Origin:  B6.Cg-Crb1rd8/Pjn
Mutation
description
Allele Type:    Chemically induced (ENU) (Humanized sequence)
Mutation:    Single point mutation
 
Mutation detailsThis ENU induced c.533A>G point transition leads to a Tyr178Cys substitution in the intradiscal region. (J:243745)
Inheritance:    Dominant
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 2 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Rho Mutation:  13 strains or lines available
References
Original:  J:243745 Krebs MP, et al., Mouse models of human ocular disease for translational research. PLoS One. 2017;12(8):e0183837
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
03/31/2020
MGI 6.15
The Jackson Laboratory