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Nalcnem1Iiis
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Nalcnem1Iiis
Name: sodium leak channel, non-selective; endonuclease-mediated mutation 1, Masashi Yanagisawa and Hiromasa Funato
MGI ID: MGI:5806546
Synonyms: CRISPR NalcnDrl, Nalcnem1Staka
Gene: Nalcn  Location: Chr14:123276634-123627144 bp, - strand  Genetic Position: Chr14, 66.04 cM
Mutation
origin
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Endonuclease-mediated (Not Specified)
Mutation:    Single point mutation
 
Mutation detailsCRISPR/Cas technology repliaced the ENU-induced mutation identified in NalcnDrl (an A to T substitution that results in an amino acid substitution at the 315th residue from asparagine to lysine (N315L)). (J:236598)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Nalcn Mutation:  6 strains or lines available
References
Original:  J:236598 Funato H, et al., Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. 2016 Nov 17;539(7629):378-383
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory