Pcdh15^m4Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pcdh15^m4Btlr
• Name: protocadherin 15; mutation 4, Bruce Beutler
• MGI ID: MGI:5806326
• Synonyms: sphere
• Gene: Pcdh15 Location: Chr10:72935174-74485569 bp, + strand Genetic Position: Chr10, 37.43 cM
• Alliance: Pcdh15^m4Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 74,624,284 (v38) on chromosome 10, or base pair 1,524,257 in the GenBank genomic region NC_000076 for the gene. The mutation corresponds to residue 4,499 in the mRNA sequence NM_023115 (variant A) within exon 31 of 35 total exons. The mutation results in an arginine (R) to tryptophan (W) substitution at position 1,360 (R1360W) in the protein. (J:236676)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pcdh15 Mutation: 132 strains or lines available

References

• Original: J:236676 Ludwig S, et al., Mutagenetix entry for sphere. MGI Direct Data Submission. 2016
• All: 1 reference(s)