Arid4b^tm1.1Mywu
Targeted Allele Detail

Summary

• Symbol: Arid4b^tm1.1Mywu
• Name: AT-rich interaction domain 4B; targeted mutation 1.1, Mei-Yi Wu
• MGI ID: MGI:5805203
• Synonyms: Arid4b^flox
• Gene: Arid4b Location: Chr13:14238334-14374188 bp, + strand Genetic Position: Chr13, 5.29 cM
• Alliance: Arid4b^tm1.1Mywu page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:233398
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A floxed neomycin resistance cassette was inserted upsteam of exon 1. An additional loxP site was inserted downstream of exon 1. Cre-mediated recombination removed the selection cassette and left exon 1 floxed. (J:233398)

Expression

In Mice Carrying this Mutation:	78 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Arid4b Mutation: 65 strains or lines available

References

• Original: J:233398 Wu RC, et al., Androgen Receptor Coactivator ARID4B Is Required for the Function of Sertoli Cells in Spermatogenesis. Mol Endocrinol. 2015 Sep;29(9):1334-46
• All: 4 reference(s)