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Prknem1Mjff
Endonuclease-mediated Allele Detail
Nomenclature
Symbol: Prknem1Mjff
Name: parkin RBR E3 ubiquitin protein ligase; endonuclease-mediated mutation 1, The Michael J Fox Foundation
MGI ID: MGI:5800702
Synonyms: Parkin W402A KI
Gene: Prkn  Location: Chr17:10840384-12063361 bp, + strand  Genetic Position: Chr17, 7.8 cM, cytoband A3.2-A3.3
Mutation
origin
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Endonuclease-mediated (Not Applicable)
Mutations:    Insertion, Nucleotide substitutions
 
Mutation detailsThe CRISPR/cas9 endonuclease mediated genome editing introduced a W402A amino acid substitution and a silent mutation into exon 11. (J:101977)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Prkn Mutation:  30 strains or lines available
References
Original:  J:101977 The Jackson Laboratory, Information obtained from The Jackson Laboratory, Bar Harbor, ME. Unpublished. 2005-2017;
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
04/13/2021
MGI 6.16
The Jackson Laboratory