Nek5^mpc234H
Chemically induced Allele Detail

Summary

• Symbol: Nek5^mpc234H
• Name: NIMA (never in mitosis gene a)-related expressed kinase 5; muta-ped-c3pde 234, Harwell
• MGI ID: MGI:5792084
• Gene: Nek5 Location: Chr8:22563632-22615069 bp, - strand Genetic Position: Chr8, 10.95 cM
• Alliance: Nek5^mpc234H page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Harwell ENU Mutagenesis

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU mutagenesis induced a c.1660G>A point mutation that results in the amino acid substitution of alanaine with threonine at position 554 (p.A554T). (J:234901)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nek5 Mutation: 38 strains or lines available

References

• Original: J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444
• All: 1 reference(s)