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Bbs10tm1.2Vmar
Targeted Allele Detail
Nomenclature
Symbol: Bbs10tm1.2Vmar
Name: Bardet-Biedl syndrome 10 (human); targeted mutation 1.2, Vincent Marion
MGI ID: MGI:5788680
Synonyms: Bbs10-
Gene: Bbs10  Location: Chr10:111298679-111301727 bp, + strand  Genetic Position: Chr10, 58.46 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227230
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsExon 2 was deleted by Cre-mediated recombination. No detectable mRNA is expressed from this allele in samples derived from kidney and eye of homozygous mice. (J:227230)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Expression
In Structures Affected by this Mutation: 7 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bbs10 Mutation:  0 strains or lines available
References
Original:  J:227230 Cognard N, et al., Comparing the Bbs10 complete knockout phenotype with a specific renal epithelial knockout one highlights the link between renal defects and systemic inactivation in mice. Cilia. 2015;4:10
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/26/2020
MGI 6.15
The Jackson Laboratory