Tg(TNFSF11)5519Edou
Transgene Detail

Summary

• Symbol: Tg(TNFSF11)5519Edou
• Name: transgene insertion 5519, Eleni Douni
• MGI ID: MGI:5788420
• Synonyms: Tg5519
• Transgene: Tg(TNFSF11)5519Edou Location: unknown
• Alliance: Tg(TNFSF11)5519Edou page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/J)F2

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(TNFSF11)5519Edou expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TNFSF11 (8600)

  Tnfsf11

  (MGI:1100089)

• Mutation details: This transgene consists of a Not I fragment of 200 kb containing the human TNFSF11 gene isolated from genomic BAC clone RP11-86N24. This is the medium copy number (10) line. (J:233240)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:233240 Rinotas V, et al., Novel genetic models of osteoporosis by overexpression of human RANKL in transgenic mice. J Bone Miner Res. 2014;29(5):1158-69
• All: 3 reference(s)