Gli3tm3.1Blnw
Targeted Allele Detail
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Symbol: |
Gli3tm3.1Blnw |
Name: |
GLI-Kruppel family member GLI3; targeted mutation 3.1, Baolin Wang |
MGI ID: |
MGI:5780889 |
Synonyms: |
Gli3delta701C |
Gene: |
Gli3 Location: Chr13:15638308-15904611 bp, + strand Genetic Position: Chr13, 5.43 cM, cytoband A2
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Alliance: |
Gli3tm3.1Blnw page
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Germline Transmission: |
Earliest citation of germline transmission:
J:199480
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Parent Cell Line: |
W4 (ES Cell)
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Strain of Origin: |
129S6/SvEvTac
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
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Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of exon 14. An additional loxP site was inserted downstream of exon 14. Flp-mediated recombination removed the selection cassette and left exon 14 floxed. Cre-mediated deletion of exon 14 produces a protein that contains the first 701 residues and 25 additional artificial residues.
(J:199480)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gli3 Mutation: |
80 strains or lines available
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Original: |
J:199480 Cao T, et al., Mouse limbs expressing only the Gli3 repressor resemble those of Sonic hedgehog mutants. Dev Biol. 2013 Jul 15;379(2):221-8 |
All: |
1 reference(s) |
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