Adcy10^tm1.2Geno
Targeted Allele Detail

Summary

• Symbol: Adcy10^tm1.2Geno
• Name: adenylate cyclase 10; targeted mutation 1.2, Genoway
• MGI ID: MGI:5779519
• Synonyms: Adcy10^del
• Gene: Adcy10 Location: Chr1:165312752-165404343 bp, + strand Genetic Position: Chr1, 72.83 cM
• Alliance: Adcy10^tm1.2Geno page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232549
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 11 thorugh 13 were flanked with an FRT-flanked neomycin resistance cassette with a 3' loxP site and an additional loxP site. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exons 11 through 13. (J:232549)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adcy10 Mutation: 83 strains or lines available

References

• Original: J:232549 Chen J, et al., Neuronal expression of soluble adenylyl cyclase in the mammalian brain. Brain Res. 2013 Jun 26;1518:1-8
• All: 1 reference(s)