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Pik3c2gtm1Ehi
Targeted Allele Detail
Nomenclature
Symbol: Pik3c2gtm1Ehi
Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; targeted mutation 1, Emilio Hirsch
MGI ID: MGI:5779504
Synonyms: Pik3c2glacZ
Gene: Pik3c2g  Location: Chr6:139614072-139969284 bp, + strand  Genetic Position: Chr6, 69.7 cM
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:223018
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Reporter)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA lacZ and floxed neomycin resistance cassette replaced most of exon 1. RT-PCR confirmed the absence of protein expression in the liver. (J:223018)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structures
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Pik3c2g Mutation:  2 strains or lines available
References
Original:  J:223018 Braccini L, et al., PI3K-C2gamma is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory