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Dvs2A/WySn
QTL Variant Detail
Nomenclature
QTL variant: Dvs2A/WySn
Name: dorsoventral vaginal septum 2; A/WySn
MGI ID: MGI:5775053
Synonyms: Dvs2B10.A-H2 H2-T18a/SgSnJ>
QTL: Dvs2  Location: unknown  Genetic Position: Chr17, Syntenic
Variant
origin
Strain of Specimen:  A/WySn
Variant
description
Allele Type:    QTL
Mutation:    Undefined
    from B10.A-H2 H2-T18/SgSnJ
Inheritance:    Not Specified
Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:103481

C57BL/10 and the B10 H2 congenic strains B10.A, B10.A(1R), B10.A(2R), B10.A(5R), B10.A(15R) and B10.A(18R) were used to map loci influencing the frequency of vitamin A induced dorsoventral vaginal septum (DVS). Female animals were examined at 6 weeks of age for the presence of DVS. The B10.A(5R) congenic exhibits this highest incidence of DVS out of all the strain studied. Adding vitamin A to the diet did not increase DVS incidence in B10.A, B10.A(1R), B10.A(5R), B10.A(15R) and B10.A(18R).

Two loci named Dvs1 and Dvs2 mapped to the H2 locus on mouse Chromosome 17. Dvs1 is proximal to H2-Ea (18.7 cM) while Dvs2 is believed to be located between Aecp (19.5 cM) and Dxcp2 (18.975 cM). Dvs1 and Dvs2 may interact to influence the DVS phenotype.

References
Original:  J:103481 Tyan ML, Effects of H-2 and dietary vitamin A on the frequency of dorsoventral vaginal septum. Proc Soc Exp Biol Med. 1993 Jun;203(2):175-8
All:  1 reference(s)

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last database update
05/10/2022
MGI 6.19
The Jackson Laboratory