About   Help   FAQ
Targeted Allele Detail
Symbol: Piezo1tm1.1Apat
Name: piezo-type mechanosensitive ion channel component 1; targeted mutation 1.1, Ardem Patapoutian
MGI ID: MGI:5762891
Synonyms: Piezo1p1-tdT, Piezo1tdT
Gene: Piezo1  Location: Chr8:123208437-123278068 bp, - strand  Genetic Position: Chr8, 71.31 cM
Germline Transmission:  Earliest citation of germline transmission: J:212179
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Allele Type:    Targeted (Reporter)
Mutation:    Insertion
Mutation detailsA tdTomato reporter gene and floxed, self-excising neomycin resistance cassette replaced the 3'UTR. The final allele lacks the neomycin resistance cassette. (J:212179)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Piezo1 Mutation:  53 strains or lines available
Original:  J:212179 Ranade SS, et al., Piezo1, a mechanically activated ion channel, is required for vascular development in mice. Proc Natl Acad Sci U S A. 2014 Jul 15;111(28):10347-52
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
MGI 6.17
The Jackson Laboratory