Bag3tm1c(EUCOMM)Hmgu
Targeted Allele Detail
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Symbol: |
Bag3tm1c(EUCOMM)Hmgu |
Name: |
BCL2-associated athanogene 3; targeted mutation 1c, Helmholtz Zentrum Muenchen GmbH |
MGI ID: |
MGI:5760384 |
Gene: |
Bag3 Location: Chr7:128125340-128148705 bp, + strand Genetic Position: Chr7, 70.26 cM
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Alliance: |
Bag3tm1c(EUCOMM)Hmgu page
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IMPC: |
Bag3 gene page |
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Dilated cardiomyopathy in Bag3tm1c(EUCOMM)Hmgu/Bag3tm1c(EUCOMM)Hmgu Tg(Myhca-cre)1Abel/0 mice
Show the 2 phenotype image(s) involving this allele.
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Mutant Cell Line: |
HEPD0556_7_B06 |
Germline Transmission: |
Earliest citation of germline transmission:
J:204739
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Parent Cell Line: |
JM8A1.N3 (ES Cell)
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Strain of Origin: |
C57BL/6N-Atm1Brd
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Project Collection: |
EUCOMM
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Allele Type: |
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Targeted (Conditional ready) |
Mutation: |
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Insertion
Vector: L1L2_Bact_P
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Mutation details: Flp-mediated excision of the parental Bag3tm1a(EUCOMM)Hmgu allele resulted in the removal of the promoter-driven neomycin selection cassette and the inserted lacZ reporter sequence, leaving behind the loxP-flanked critical exon(s). Further information on targeting strategies used for this and other IKMC alleles can be found at http://www.informatics.jax.org/mgihome/nomen/IKMC_schematics.shtml.
(J:204739)
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View phenotypes and curated references for all genotypes (concatenated display).
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Original: |
J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023; |
All: |
6 reference(s) |
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