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Dynll1tm1.1Jhh
Targeted Allele Detail
Summary
Symbol: Dynll1tm1.1Jhh
Name: dynein light chain LC8-type 1; targeted mutation 1.1, Jorg Heierhorst
MGI ID: MGI:5755433
Synonyms: Dynll1fl
Gene: Dynll1  Location: Chr5:115435129-115438995 bp, - strand  Genetic Position: Chr5, 56.04 cM, cytoband F
Alliance: Dynll1tm1.1Jhh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:230105
Parent Cell Line:  ART B6 3.6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Mutation
description
Allele Type:    Targeted (Conditional ready)
Mutation:    Insertion
 
Mutation detailsThe promoter, exon 1 and exon 2 were floxed. Flp-mediated recombination removed the puromycin resistance cassette and left and FRT site upstream of the second loxP site in intron 2. (J:230105)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 4 strains available      Cell Lines: 0 lines available
Carrying any Dynll1 Mutation:  18 strains or lines available
References
Original:  J:230105 Wong DM, et al., The Transcription Factor ASCIZ and Its Target DYNLL1 Are Essential for the Development and Expansion of MYC-Driven B Cell Lymphoma. Cell Rep. 2016 Feb 16;14(6):1488-99
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory