Napepld^tm1.2Rpa
Targeted Allele Detail

Summary

• Symbol: Napepld^tm1.2Rpa
• Name: N-acyl phosphatidylethanolamine phospholipase D; targeted mutation 1.2, Richard D Palmiter
• MGI ID: MGI:5755167
• Synonyms: Napepld^lox
• Gene: Napepld Location: Chr5:21867899-21906394 bp, - strand Genetic Position: Chr5, 9.97 cM
• Alliance: Napepld^tm1.2Rpa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:221888
• Parent Cell Line: AK18.1 (ES Cell)
• Strain of Origin: 129S4/SvJaeSor

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: LoxP sites flank exon 3. An Sv-Neo (SV40 promoter-neomycinphosphotransferase) gene is flanked by frt sites then removed by flp mediated recombination. (J:132692, J:221888)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Napepld Mutation: 25 strains or lines available

References

• Original: J:221888 Geurts L, et al., Adipose tissue NAPE-PLD controls fat mass development by altering the browning process and gut microbiota. Nat Commun. 2015;6:6495
• All: 5 reference(s)