Otud5^tm1Vmd
Targeted Allele Detail

Summary

• Symbol: Otud5^tm1Vmd
• Name: OTU domain containing 5; targeted mutation 1, Vishva M Dixit
• MGI ID: MGI:5752247
• Synonyms: Duba^fl
• Gene: Otud5 Location: ChrX:7707603-7742865 bp, + strand Genetic Position: ChrX, 3.54 cM
• Alliance: Otud5^tm1Vmd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229517
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 2 and an FRT flanked neo cassette and loxP site were inserted downstream of exon 2 via homologous recombination. (J:219495, J:229517)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Otud5 Mutation: 8 strains or lines available

References

• Original: J:229517 Huang OW, et al., Phosphorylation-dependent activity of the deubiquitinase DUBA. Nat Struct Mol Biol. 2012 Feb;19(2):171-5
• All: 2 reference(s)