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Mir142tm1.1Sbel
Targeted Allele Detail
Summary
Symbol: Mir142tm1.1Sbel
Name: microRNA 142; targeted mutation 1.1, Saverio Bellusci
MGI ID: MGI:5752051
Gene: Mir142  Location: Chr11:87647690-87647753 bp, + strand  Genetic Position: Chr11, 52.21 cM
Alliance: Mir142tm1.1Sbel page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227228
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  C57BL/6N
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsThe microRNA sequence was replaced with a floxed neomycin resistance and Protamine-cre cassette. The final allele lacks the selection cassette and cre recombinase gene. (J:227228)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Mir142 Mutation:  2 strains or lines available
References
Original:  J:227228 Shrestha A, et al., Generation and Validation of miR-142 Knock Out Mice. PLoS One. 2015;10(9):e0136913
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory