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Tg(tetO-FMR1*,-EGFP)#Rkhu
Transgene Detail
Nomenclature
Symbol: Tg(tetO-FMR1*,-EGFP)#Rkhu
Name: transgene insertion, Renate K Hukema
MGI ID: MGI:5751860
Synonyms: 90CGG, TRE-90CGC-eGFP
Transgene: Tg(tetO-FMR1*,-EGFP)#Rkhu  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6JRj
Transgene
description
Transgene Type:    Transgenic (Humanized sequence, Inducible, Inserted expressed sequence, Reporter)
Inducer:    induced by tTA
Mutation:    Insertion
 
Tg(tetO-FMR1*,-EGFP)#Rkhu expresses 1 gene
 
Mutation detailsHuman FMR1 5' UTR containing 90 CGG repeats and enhanced green fluorescent protein are under the control of the tetracycline responsive promoter element. (J:229379)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Disease models
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:229379 Hukema RK, et al., Induced expression of expanded CGG RNA causes mitochondrial dysfunction in vivo. Cell Cycle. 2014;13(16):2600-8
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
02/23/2021
MGI 6.16
The Jackson Laboratory