Zfp36tm2.1Pjb
Targeted Allele Detail
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Symbol: |
Zfp36tm2.1Pjb |
Name: |
zinc finger protein 36; targeted mutation 2.1, Perry J Blackshear |
MGI ID: |
MGI:5750624 |
Synonyms: |
TTPdeltaARE |
Gene: |
Zfp36 Location: Chr7:28076208-28078680 bp, - strand Genetic Position: Chr7, 16.72 cM
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Alliance: |
Zfp36tm2.1Pjb page
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Germline Transmission: |
Earliest citation of germline transmission:
J:229078
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6
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Allele Type: |
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Targeted (Not Applicable) |
Mutation: |
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Intragenic deletion
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Mutation details: The targeting vector deletes 136 bp in the 3 UTR of the gene. The vector contains a loxP site, a wild type exon 2, an FRT-flanked neomycin cassette, a second loxP site and a mutant exon 2 containing the 136 bp deletion. Cre-mediated recombination removed the wild-type exon 2 and the neomycin cassette.
(J:229078)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Zfp36 Mutation: |
16 strains or lines available
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Original: |
J:229078 Patial S, et al., Enhanced stability of tristetraprolin mRNA protects mice against immune-mediated inflammatory pathologies. Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1865-70 |
All: |
3 reference(s) |
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