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Tg(Tek-Npr1)#Kkan
Transgene Detail
Nomenclature
Symbol: Tg(Tek-Npr1)#Kkan
Name: transgene insertion, Kenji Kangawa
MGI ID: MGI:5750460
Synonyms: EC GC-A-Tg
Transgene: Tg(Tek-Npr1)#Kkan  Location: unknown  
Transgene
origin
Strain of Origin:  C57BL/6
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Tek-Npr1)#Kkan expresses 1 gene
 
Mutation detailsA 12.1 kb fragment of the mouse Tek gene including the promoter, enhancer and exons 1-3 of the 5' UTR drives expression of a mouse Npr1 cDNA in the vascular endothelium. (J:220676)
Schematic diagram of the construct used to produce the Tg(Tek-Npr1)#Kkan trangenic mouse
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:220676 Nojiri T, et al., Atrial natriuretic peptide prevents cancer metastasis through vascular endothelial cells. Proc Natl Acad Sci U S A. 2015 Mar 31;112(13):4086-91
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory